Article
Mitochondrial DNA variation analysis in cervical cancer.
Mitochondrion - 1 May 2014
Kabekkodu Shama Prasada, Bhat Samatha, Mascarenhas Roshan, Mallya Sandeep, Bhat Manoj, Pandey Deeksha, Kushtagi Pralhad, Thangaraj Kumarasamy, Gopinath P M, Satyamoorthy Kapaettu
Abstract excerpt
This study was undertaken to investigate the mitochondrial DNA (mtDNA) variation in non-malignant and malignant cervical tissue samples. We have identified 229 and 739 variations non-malignant and malignant tissues respectively distributed over 321 locations in the D-loop (50 in non-malignant and 166 in malignant; 216 variations), coding region (139 in non-malignant and 455 in malignant; 594 variations) tRNA and...
Topics
- Aged
- Biostatistics
- Computational Biology
- DNA, Mitochondrial
- Female
- Humans
- Middle Aged
- Mutation
- Sequence Analysis, DNA
- Uterine Cervical Neoplasms
