Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genetic markers of treatment response to tumour necrosis factor-α inhibitors in the treatment of psoriasis.

Clinical and experimental dermatology - 1 Jun 2014

Ryan C, Kelleher J, Fagan M F, Rogers S, Collins P, Barker J N W N, Allen M, Hagan R, Renfro L, Kirby B

Abstract excerpt

BACKGROUND: Anti-tumour necrosis factor (TNF)-α therapies have revolutionized the treatment of psoriasis; however, up to 50% of patients do not respond satisfactorily. Identification of pharmacogenetic markers of treatment response is an important stop in the development of individually tailored treatment. The objective of this study was to assess the association of human leucocyte antigen (HLA)-C, killer...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adalimumab
Share to Anti-Inflammatory Agents

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Antibodies, Monoclonal, Humanized

Share to Etanercept

Share to HLA-C Antigens

Share to Psoriasis

Share to Receptors, KIR

Share to Receptors, Tumor Necrosis Factor

Source

Identifiers

PMID: 24758522
DOI: 10.1111/ced.12323

Genes

VDR
TNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genetic markers of treatment response to tumour necrosis factor-α inhibitors in the treatment of psoriasis.PMID 24758522Read ↗

Genetic prediction of the effectiveness of biologics for psoriasis treatment.Semantic proximity Read ↗

Genetic Influence on Treatment Response in Psoriasis: New Insights into Personalized Medicine.Semantic proximity Read ↗

Do genetics contribute to TNF inhibitor response prediction in Psoriatic Arthritis?Semantic proximity Read ↗

Influence of Genetic Polymorphisms on Response to Biologics in Moderate-to-Severe PsoriasisSemantic proximity Read ↗

Pharmacogenomics on the Treatment Response in Patients with Psoriasis: An Updated ReviewSemantic proximity Read ↗

Genome-wide association analysis of psoriasis patients treated with anti-TNF drugs.Semantic proximity Read ↗

Pharmacogenetic analysis of TNF, TNFRSF1A, and TNFRSF1B gene polymorphisms and prediction of response to anti-TNF therapy in psoriasis patients in the Greek population.Semantic proximity Read ↗

New polymorphisms associated with response to anti-TNF drugs in patients with moderate-to-severe plaque psoriasis.Semantic proximity Read ↗

Association between several immune response-related genes and the effectiveness of biological treatments in patients with moderate-to-severe psoriasis.Semantic proximity Read ↗

Impact of pharmacogenomics upon the therapeutic response to etanercept in psoriasis and psoriatic arthritis.Semantic proximity Read ↗

TNF-alpha gene polymorphisms can help to predict response to etanercept in psoriatic patients.Semantic proximity Read ↗

Genetic polymorphisms to identify patients with an optimal response to tildrakizumab in psoriasis patients from real-life clinical practice.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.