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Article

TNF-alpha gene polymorphisms can help to predict response to etanercept in psoriatic patients.

Journal of the European Academy of Dermatology and Venereology : JEADV - 1 Sept 2015

De Simone C, Farina M, Maiorino A, Fanali C, Perino F, Flamini A, Caldarola G, Sgambato A

Abstract excerpt

BACKGROUND: Genetic factors might have a role for lack of therapeutic response to anti-TNF-alpha agents, as previously suggested in patients with rheumatoid arthritis and inflammatory bowel disease. OBJECTIVES: We evaluated the role of the main TNF-alpha polymorphisms (-238G>A, -308G>A, -857C>T) in predicting the response to etanercept, an anti-TNF-alpha fusion protein. MATERIAL AND METHODS: Genomic DNA was...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 25726968
DOI: 10.1111/jdv.13024

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TNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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