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Article

Association between several immune response-related genes and the effectiveness of biological treatments in patients with moderate-to-severe psoriasis.

Experimental dermatology - 1 Jan 2024

Loras Alba, Gil-Barrachina Marta, Hernando Barbara, Perez-Pastor Gemma, Martinez-Domenech Alvaro, Mahiques Laura, Pitarch Gerard, Valcuende-Cavero Francisca, Ballester-Sanchez Rosa, Marques-Torrejon Maria Angeles, Martinez-Cadenas Conrado

Abstract excerpt

Biological therapies are safer and more effective against psoriasis than conventional treatments. Even so, 30-50% of psoriatic patients show an inadequate response, which is associated with individual genetic heterogeneity. Pharmacogenetic studies have identified several single nucleotide polymorphisms (SNPs) as possible predictive and prognostic biomarkers for psoriasis treatment response. The objective of this...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 38284189
DOI: 10.1111/exd.15003

Genes

IL12B
PGLYRP4
SLC12A8
TIRAP
TLR2
TLR5
TNF
TNFAIP3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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