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Article

Genetic prediction of the effectiveness of biologics for psoriasis treatment.

The Journal of dermatology - 1 Nov 2016

Nishikawa Rika, Nagai Hiroshi, Bito Toshinori, Ikeda Tetsuya, Horikawa Tatsuya, Adachi Atsuko, Matsubara Tsukasa, Nishigori Chikako

Abstract excerpt

Anti-tumor necrosis factor (TNF)-α therapy is used for the treatment of psoriasis, with varying outcomes. However, the specific cause of inadequate response or treatment failure remains unknown. The aim of the present study was to identify useful clinical biomarkers for predicting therapeutic responses or to serve as new drug targets for refractory psoriasis cases. We performed a genome-wide association study...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 27129929
DOI: 10.1111/1346-8138.13412

Genes

TNF
JAG2
TLR10

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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