Article
Genetic Influence on Treatment Response in Psoriasis: New Insights into Personalized Medicine.
International journal of molecular sciences - 7 Jun 2023
Berna-Rico Emilio, Perez-Bootello Javier, Abbad-Jaime de Aragon Carlota, Gonzalez-Cantero Alvaro
Abstract excerpt
Psoriasis is a chronic inflammatory disease with an established genetic background. The HLA-Cw*06 allele and different polymorphisms in genes involved in inflammatory responses and keratinocyte proliferation have been associated with the development of the disease. Despite the effectiveness and safety of psoriasis treatment, a significant percentage of patients still do not achieve adequate disease control....
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