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Article

The TRPP subfamily and polycystin-1 proteins.

Handbook of experimental pharmacology - 1 Jan 2014

Semmo Mariam, Köttgen Michael, Hofherr Alexis

Abstract excerpt

It has been exciting times since the identification of polycystic kidney disease 1 (PKD1) and PKD2 as the genes mutated in autosomal dominant polycystic kidney disease (ADPKD). Biological roles of the encoded proteins polycystin-1 and TRPP2 have been deduced from phenotypes in ADPKD patients, but recent insights from vertebrate and invertebrate model organisms have significantly expanded our understanding of the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 24756726
DOI: 10.1007/978-3-642-54215-2_27

Genes

PKD1
PKD2
PKDREJ

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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