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Genetics and Pathogenesis of Polycystic Kidney Disease

1 Sept 2002

Abstract excerpt

Polycystic kidney disease (PKD), a common genetic cause of chronic renal failure in children and adults, is characterized by the accumulation of fluid-filled cysts in the kidney and other organs. The renal cysts originate from the epithelia of the nephrons and renal collecting system and are lined by a single layer of cells that have higher rates of cellular proliferation and are less differentiated than normal...

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PMID: 12191984
DOI: 10.1097/01.asn.0000028643.17901.42

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