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Article

TRP channels and kidney disease: lessons from polycystic kidney disease

22 Jan 2007

Abstract excerpt

Important insights in to the function of members of the TRP (transient receptor potential) channel superfamily have been gained from the identification of disease-related mutations. In particular the identification of mutations in the PKD2 gene in autosomal dominant polycystic kidney disease has revealed a link between TRP channel function, mechanosensation and the role of the primary cilium in renal cyst...

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Identifiers

PMID: 17233617
DOI: 10.1042/bst0350124

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Related research

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TRP channels and kidney disease: lessons from polycystic kidney diseasePMID 17233617Read ↗

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The functions of TRPP2 in the vascular system.Semantic proximity Read ↗

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