Article
Association of MASP-2 levels and MASP2 gene polymorphisms with rheumatoid arthritis in patients and their relatives.
PloS one - 1 Jan 2014
Goeldner Isabela, Skare Thelma, Boldt Angelica B W, Nass Flavia R, Messias-Reason Iara J, Utiyama Shirley R
Abstract excerpt
BACKGROUND: Mannan-binding lectin-associated serine protease 2 (MASP-2) is a key protein of the lectin pathway of complement. MASP-2 levels have been associated with different polymorphisms within MASP2 gene as well as with the risk for inflammatory disorders and infections. Despite its clinical importance, MASP-2 remains poorly investigated in rheumatoid arthritis (RA). METHODS: In this case-control study, we...
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