Article
Fission yeast Rad52 phosphorylation restrains error prone recombination pathways.
PloS one - 1 Jan 2014
Bellini Angela, Girard Pierre-Marie, Tessier Ludovic, Sage Evelyne, Francesconi Stefania
Abstract excerpt
Rad52 is a key protein in homologous recombination (HR), a DNA repair pathway dedicated to double strand breaks and recovery of blocked or collapsed replication forks. Rad52 allows Rad51 loading on single strand DNA, an event required for strand invasion and D-loop formation. In addition, Rad52 functions also in Rad51 independent pathways because of its ability to promote single strand annealing (SSA) that leads...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
