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Article

Mus81 functions in the quality control of replication forks at the rDNA and is involved in the maintenance of rDNA repeat number in Saccharomyces cerevisiae.

Mutation research - 1 Dec 2007

Ii Miki, Ii Tatsuya, Brill Steven J

Abstract excerpt

Previous studies in yeast have suggested that the SGS1 DNA helicase or the Mus81-Mms4 structure-specific endonuclease is required to suppress the accumulation of lethal recombination intermediates during DNA replication. However, the structure of these intermediates and their mechanism of the suppression are unknown. To examine this reaction, we have isolated and characterized a temperature-sensitive (ts) allele...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Rad52 DNA Repair and Recombination Protein

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Source

Open in PubMed Open full text

Identifiers

PMID: 17555773
DOI: 10.1016/j.mrfmmm.2007.04.007
PMCID: PMC2100401

Genes

RAD52
MUS81

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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Mus81 functions in the quality control of replication forks at the rDNA and is involved in the maintenance of rDNA repeat number in Saccharomyces cerevisiae.PMID 17555773Read ↗

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