Article
Ionizing radiation-induced foci formation of mammalian Rad51 and Rad54 depends on the Rad51 paralogs, but not on Rad52.
Mutation research - 1 Jul 2005
van Veelen Lieneke R, Essers Jeroen, van de Rakt Mandy W M M, Odijk Hanny, Pastink Albert, Zdzienicka Małgorzata Z, Paulusma Coen C, Kanaar Roland
Abstract excerpt
Homologous recombination is of major importance for the prevention of genomic instability during chromosome duplication and repair of DNA damage, especially double-strand breaks. Biochemical experiments have revealed that during the process of homologous recombination the RAD52 group proteins, including Rad51, Rad52 and Rad54, are involved in an essential step: formation of a joint molecule between the broken DNA...
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