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Article

Nonsense-mediated decay regulates key components of homologous recombination.

Nucleic acids research - 20 Jun 2016

Janke Ryan, Kong Jeremy, Braberg Hannes, Cantin Greg, Yates John R, Krogan Nevan J, Heyer Wolf-Dietrich

Abstract excerpt

Cells frequently experience DNA damage that requires repair by homologous recombination (HR). Proteins involved in HR are carefully coordinated to ensure proper and efficient repair without interfering with normal cellular processes. In Saccharomyces cerevisiae, Rad55 functions in the early steps of HR and is regulated in response to DNA damage through phosphorylation by the Mec1 and Rad53 kinases of the DNA...

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Source

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Identifiers

PMID: 27001511
DOI: 10.1093/nar/gkw182
PMCID: PMC4914092

Genes

RAD51

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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