Article

Differentiating Drosophila female germ cells initiate Polycomb silencing by altering PRC2 sampling

2020-02-04

Abstract excerpt

<h4>Summary</h4> Polycomb silencing represses gene expression and provides a molecular memory of chromatin state that is essential for animal development. We show that Drosophila female germline stem cells (GSCs) provide a powerful system for studying Polycomb silencing and how it is established. GSCs resemble pluripotent mammalian embryonic cells in lacking silenced chromatin, but most GSC daughters, like typic...

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Literature Corpus work: 636d8bd1-d5cb-55c7-a23d-5b8f2e7f33ff
DOI: 10.1101/2020.02.03.932582

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