Article
Genome-wide diet-gene interaction analyses for risk of colorectal cancer.
PLoS genetics - 1 Apr 2014
Figueiredo Jane C, Hsu Li, Hutter Carolyn M, Lin Yi, Campbell Peter T, Baron John A, Berndt Sonja I, Jiao Shuo, Casey Graham, Fortini Barbara, Chan Andrew T, Cotterchio Michelle, Lemire Mathieu, Gallinger Steven, Harrison Tabitha A, Le Marchand Loic, Newcomb Polly A, Slattery Martha L, Caan Bette J, Carlson Christopher S, Zanke Brent W, Rosse Stephanie A, Brenner Hermann, Giovannucci Edward L, Wu Kana, Chang-Claude Jenny, Chanock Stephen J, Curtis Keith R, Duggan David, Gong Jian, Haile Robert W, Hayes Richard B, Hoffmeister Michael, Hopper John L, Jenkins Mark A, Kolonel Laurence N, Qu Conghui, Rudolph Anja, Schoen Robert E, Schumacher Fredrick R, Seminara Daniela, Stelling Deanna L, Thibodeau Stephen N, Thornquist Mark, Warnick Greg S, Henderson Brian E, Ulrich Cornelia M, Gauderman W James, Potter John D, White Emily, Peters Ulrike
Abstract excerpt
Dietary factors, including meat, fruits, vegetables and fiber, are associated with colorectal cancer; however, there is limited information as to whether these dietary factors interact with genetic variants to modify risk of colorectal cancer. We tested interactions between these dietary factors and approximately 2.7 million genetic variants for colorectal cancer risk among 9,287 cases and 9,117 controls from ten...
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