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Article

Genome-wide investigation of gene-environment interactions in colorectal cancer.

Human genetics - 1 Feb 2013

Siegert Sabine, Hampe Jochen, Schafmayer Clemens, von Schönfels Witigo, Egberts Jan-Hendrik, Försti Asta, Chen Bowang, Lascorz Jesús, Hemminki Kari, Franke Andre, Nothnagel Michael, Nöthlings Ute, Krawczak Michael

Abstract excerpt

Colorectal cancer (CRC), one of the most frequent neoplasias worldwide, has both genetic and environmental causes. As yet, however, gene-environment (G × E) interactions in CRC have been studied mostly for a small number of candidate genes only. Therefore, we investigated the possible interaction, in CRC etiology, between single-nucleotide polymorphisms (SNPs) on the one hand, and overweight, smoking and alcohol...

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Identifiers

PMID: 23114982
DOI: 10.1007/s00439-012-1239-2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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