Article
Genetic variants in the genes of the stress hormone signalling pathway and depressive symptoms during and after pregnancy.
BioMed research international - 1 Jan 2014
Schneider Michael, Engel Anne, Fasching Peter A, Häberle Lothar, Binder Elisabeth B, Voigt Franziska, Grimm Jennifer, Faschingbauer Florian, Eichler Anna, Dammer Ulf, Rebhan Dirk, Amann Manuela, Raabe Eva, Goecke Tamme W, Quast Carina, Beckmann Matthias W, Kornhuber Johannes, Seifert Anna, Burghaus Stefanie
Abstract excerpt
PURPOSE: The aim of this study was to investigate whether single nucleotide polymorphisms (SNPs) in genes of the stress hormone signaling pathway, specifically FKBP5, NR3C1, and CRHR1, are associated with depressive symptoms during and after pregnancy. METHODS: The Franconian Maternal Health Evaluation Study (FRAMES) recruited healthy pregnant women prospectively for the assessment of maternal and fetal health...
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