Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Glucocorticoid receptor gene haplotype predicts increased risk of hospital admission for depressive disorders in the Helsinki birth cohort study.

Journal of psychiatric research - 1 Sept 2011

Lahti Jari, Räikkönen Katri, Bruce Sara, Heinonen Kati, Pesonen Anu-Katariina, Rautanen Anna, Wahlbeck Kristian, Kere Juha, Kajantie Eero, Eriksson Johan G

Abstract excerpt

BACKGROUND: Although glucocorticoid receptors (GR) are involved in mediating hypothalamic-pituitary-adrenal-axis functioning, which is altered in acute depression, data on associations between GR gene (NR3C1) polymorphisms and depression are scarce. We examined if single nucleotide polymorphisms (SNPs) and their haplotypes spanning the entire NR3C1 are associated with depressive disorders and with self-reported...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Confidence Intervals
Share to Depressive Disorder

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Finland

Share to Likelihood Functions

Share to Predictive Value of Tests

Share to Psychiatric Status Rating Scales

Share to Receptors, Glucocorticoid

Share to Self Report

Source

Identifiers

PMID: 21477816
DOI: 10.1016/j.jpsychires.2011.03.008

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Glucocorticoid receptor gene haplotype predicts increased risk of hospital admission for depressive disorders in the Helsinki birth cohort study.PMID 21477816Read ↗

Characterization of a glucocorticoid receptor gene (GR, NR3C1) promoter polymorphism reveals functionality and extends a haplotype with putative clinical relevance.Semantic proximity Read ↗

The sex-dependent role of the glucocorticoid receptor in depression: variations in the NR3C1 gene are associated with major depressive disorder in women but not in men.Semantic proximity Read ↗

Unipolar depression and hippocampal volume: impact of DNA sequence variants of the glucocorticoid receptor gene.Semantic proximity Read ↗

Mutation screen and association analysis of the glucocorticoid receptor gene (NR3C1) in childhood-onset mood disorders (COMD).Semantic proximity Read ↗

Glucocorticoid receptor gene-based SNP analysis in patients with recurrent major depression.Semantic proximity Read ↗

Glucocorticoid receptor polymorphism is associated with major depression and predominance of depression in the course of bipolar disorder.Semantic proximity Read ↗

Single nucleotide polymorphisms of NR3C1 gene and recurrent depressive disorder in population of Poland.Semantic proximity Read ↗

Glucocorticoid receptor gene (NR3C1) promoter is hypermethylated in Thai females with major depressive disorder.Semantic proximity Read ↗

Evidence for the involvement of the glucocorticoid receptor gene in bipolar disorder in an isolated northern Swedish population.Semantic proximity Read ↗

Association of glucocorticoid and type 1 corticotropin-releasing hormone receptors gene variants and risk for depression during pregnancy and post-partum.Semantic proximity Read ↗

Methylation of the leukocyte glucocorticoid receptor gene promoter in adults: associations with early adversity and depressive, anxiety and substance-use disordersSemantic proximity Read ↗

Association between genetic variants and depression in a Romanian cohort.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.