Article
Genetic variants in the glucocorticoid pathway genes and birth weight.
Archives of gynecology and obstetrics - 1 Feb 2021
Schneider Michael O, Hübner Theresa, Pretscher Jutta, Goecke Tamme W, Schwitulla Judith, Häberle Lothar, Kornhuber Johannes, Ekici Arif B, Beckmann Matthias W, Fasching Peter A, Schwenke Eva
Abstract excerpt
PURPOSE: The aim of this study was to examine associations between single nucleotide polymorphisms (SNPs) that tag genetic variation in the glucocorticoid pathways (particularly in maternal genes FKBP5, NR3C1, and CRHR1) and birth weight. METHODS: The Franconian Maternal Health Evaluation Study (FRAMES) recruited healthy pregnant women prospectively for the assessment of maternal and fetal health. Germline DNA...
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