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Article

Genetic variants in the genes of the sex steroid hormone metabolism and depressive symptoms during and after pregnancy.

Archives of gynecology and obstetrics - 1 Jun 2023

Schneider Michael O, Pretscher Jutta, Goecke Tamme W, Häberle Lothar, Engel Anne, Kornhuber Johannes, Eichler Anna, Ekici Arif B, Beckmann Matthias W, Fasching Peter A, Schwenke Eva

Abstract excerpt

PURPOSE: The aim of this study was to conduct an association analysis of depressive symptoms and polymorphisms in the ESR1, PGR, CYP19A1, and COMT genes in pregnant and postpartum women. METHODS: The Franconian Maternal Health Evaluation Study (FRAMES) recruited healthy pregnant women prospectively for assessment of maternal and fetal health. The German version of the 10-item Edinburgh Postnatal Depression Scale...

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PMID: 35680688
DOI: 10.1007/s00404-022-06644-8

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