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Article

Three-way interaction effects of early life stress, positive parenting and FKBP5 in the development of depressive symptoms in a general population.

Journal of neural transmission (Vienna, Austria : 1996) - 1 Sept 2021

Keijser Rebecka, Olofsdotter Susanne, Nilsson Kent W, Åslund Cecilia

Abstract excerpt

FKBP5 gene-environment interaction (cG × E) studies have shown diverse results, some indicating significant interaction effects between the gene and environmental stressors on depression, while others lack such results. Moreover, FKBP5 has a potential role in the diathesis stress and differential susceptibility theorem. The aim of the present study was to evaluate whether a cG × E interaction effect of FKBP5...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 34423378
DOI: 10.1007/s00702-021-02405-0
PMCID: PMC8423649

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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