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Article

A modified screening system for loss-of-function and dominant negative alleles of essential MCMV genes.

PloS one - 1 Jan 2014

Pogoda Madlen, Bosse Jens B, Conzelmann Karl-Klaus, Koszinowski Ulrich H, Ruzsics Zsolt

Abstract excerpt

Inactivation of gene products by dominant negative mutants is a valuable tool to assign functions to yet uncharacterized proteins, to map protein-protein interactions or to dissect physiological pathways. Detailed functional and structural knowledge about the target protein would allow the constr...

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Identifiers

PMID: 24733555
DOI: 10.1371/journal.pone.0094918
PMCID: PMC3986410

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-24733555-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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