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Article

Development of a system for discovery of genetic interactions for essential genes in Escherichia coli K-12.

Genes & genetic systems - 1 Jan 2013

Yong Han Tek, Yamamoto Natsuko, Takeuchi Rikiya, Hsieh Yi-Ju, Conrad Tom M, Datsenko Kirill A, Nakayashiki Toru, Wanner Barry L, Mori Hirotada

Abstract excerpt

Genetic interaction networks are especially useful for functional assignment of genes and gaining new insights into the systems-level organization of the cell. While studying interactions of nonessential genes can be relatively straight-forward via use of deletion mutants, different approaches must be used to reveal interactions of essential genes due to their indispensability. One method shown to be useful for...

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Identifiers

PMID: 24463526
DOI: 10.1266/ggs.88.233

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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