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M94 Is Essential for the Secondary Envelopment of Murine Cytomegalovirus

30 Jun 2011

Abstract excerpt

The gene M94 of murine cytomegalovirus (MCMV) as well as its homologues UL16 in alphaherpesviruses is involved in viral morphogenesis. For a better understanding of its role in the viral life cycle, a library of random M94 mutants was generated by modified transposon-based linker scanning mutagenesis. A comprehensive set of M94 mutants was reinserted into the MCMV genome and tested for their capacity to...

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PMID: 21715482
DOI: 10.1128/jvi.00443-11

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