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Article

Characterization of conserved region 2-deficient mutants of the cytomegalovirus egress protein pM53.

Journal of virology - 1 Dec 2012

Pogoda Madlen, Bosse Jens B, Wagner Felicia M, Schauflinger Martin, Walther Paul, Koszinowski Ulrich H, Ruzsics Zsolt

Abstract excerpt

Dominant-negative (DN) mutants are powerful tools for studying essential protein-protein interactions. A systematic genetic screen of the essential murine cytomegalovirus (MCMV) protein pM53 identified the accumulation of inhibitory mutations within conserved region 2 (CR2) and CR4. The strong in...

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Identifiers

PMID: 22993161
DOI: 10.1128/JVI.00471-12
PMCID: PMC3497646

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22993161-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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