Article
Genetic analysis of cytomegalovirus by shuttle mutagenesis.
Methods in molecular biology (Clifton, N.J.) - 1 Jan 2005
Lee Manfred, Liu Fenyong
Abstract excerpt
The genomes of Herpesviridae family members are among the largest of all viruses and therefore present a formidable challenge in understanding the roles of every gene in replication or pathogenesis. For example, murine cytomegalovirus (MCMV) has a genome of 230 kb that encodes more than 170 genes, many of which have unknown functions. Many techniques for the genetic analysis of a herpesvirus have been developed...
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