Article
Estrogen receptor α variants affect age at onset of Alzheimer's disease in a multiethnic female cohort.
Dementia and geriatric cognitive disorders - 1 Jan 2014
Janicki S C, Park N, Cheng R, Clark L N, Lee J H, Schupf N
Abstract excerpt
BACKGROUND/AIMS: Few studies of gene variants that affect estrogen activity investigate their association with age at onset of Alzheimer's disease (AD) in women of different ethnicities. We examined the influence of ESR1 polymorphisms on age at onset of AD in a multiethnic cohort of women. METHODS: Among 1,436 women participating in the Washington Heights Inwood Columbia Aging Project, association with age at AD...
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