Article
The genotype-phenotype map of yeast complex traits: basic parameters and the role of natural selection.
Molecular biology and evolution - 1 Jun 2014
Ho Wei-Chin, Zhang Jianzhi
Abstract excerpt
Most phenotypic traits are controlled by many genes, but a global picture of the genotype-phenotype map (GPM) is lacking. For example, in no species do we know generally how many genes affect a trait and how large these effects are. It is also unclear to what extent GPMs are shaped by natural selection. Here we address these fundamental questions using the reverse genetic data of 220 morphological traits in 4,718...
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