Genetic complexity and quantitative trait loci mapping of yeast morphological traits.

Abstract excerpt

Functional genomics relies on two essential parameters: the sensitivity of phenotypic measures and the power to detect genomic perturbations that cause phenotypic variations. In model organisms, two types of perturbations are widely used. Artificial mutations can be introduced in virtually any gene and allow the systematic analysis of gene function via mutants fitness. Alternatively, natural genetic variations...

Topics

• Cell Size
• Chromosome Mapping
• GTP-Binding Protein alpha Subunits
• GTP-Binding Protein alpha Subunits, Gq-G11
• Gene Deletion
• Gene Expression Regulation
• Genetic Variation
• Models, Biological
• Polymorphism, Single Nucleotide
• Quantitative Trait Loci