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Article

Detecting genetic interactions in pathway-based genome-wide association studies.

Genetic epidemiology - 1 May 2014

Huang Anhui, Martin Eden R, Vance Jeffery M, Cai Xiaodong

Abstract excerpt

Pathway-based genome-wide association studies (GWAS) can exploit collective effects of causal variants in a pathway to increase power of detection. However, current methods for pathway-based GWAS do not consider epistatic effects of genetic variants, although interactions between genetic variants may play an important role in influencing complex traits. In this paper, we employed a Bayesian Lasso logistic...

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PMID: 24719383
DOI: 10.1002/gepi.21803

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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