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Article

Gene and pathway-based second-wave analysis of genome-wide association studies.

European journal of human genetics : EJHG - 1 Jan 2010

Peng Gang, Luo Li, Siu Hoicheong, Zhu Yun, Hu Pengfei, Hong Shengjun, Zhao Jinying, Zhou Xiaodong, Reveille John D, Jin Li, Amos Christopher I, Xiong Momiao

Abstract excerpt

Despite the great success of genome-wide association studies (GWAS) in identification of the common genetic variants associated with complex diseases, the current GWAS have focused on single-SNP analysis. However, single-SNP analysis often identifies only a few of the most significant SNPs that account for a small proportion of the genetic variants and offers only a limited understanding of complex diseases. To...

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Identifiers

PMID: 19584899
DOI: 10.1038/ejhg.2009.115
PMCID: PMC2987176

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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