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Article

Two novel pathway analysis methods based on a hierarchical model.

Bioinformatics (Oxford, England) - 1 Mar 2014

Evangelou Marina, Dudbridge Frank, Wernisch Lorenz

Abstract excerpt

MOTIVATION: Over the past few years several pathway analysis methods have been proposed for exploring and enhancing the analysis of genome-wide association data. Hierarchical models have been advocated as a way to integrate SNP and pathway effects in the same model, but their computational complexity has prevented them being applied on a genome-wide scale to date. METHODS: We present two novel methods for...

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Identifiers

PMID: 24123673
DOI: 10.1093/bioinformatics/btt583
PMCID: PMC3933872

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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