Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

African ancestry influences CCR5 -2459G>A genotype-associated virologic success of highly active antiretroviral therapy.

Journal of acquired immune deficiency syndromes (1999) - 1 May 2014

Cheruvu Vinay K, Igo Robert P, Jurevic Richard J, Serre David, Zimmerman Peter A, Rodriguez Benigno, Mehlotra Rajeev K

Abstract excerpt

INTRODUCTION: In a North American, HIV-positive, highly active antiretroviral therapy (HAART)-treated, adherent cohort of self-identified white and black patients, we previously observed that chemokine (C-C motif) receptor 5 (CCR5) -2459G>A genotype had a strong association with time to achieve virologic success (TVLS) in black but not in white patients. METHODS: Using 128 genome-wide ancestry informative...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Anti-Retroviral Agents
Share to Antiretroviral Therapy, Highly Active

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Black or African American

Share to Cohort Studies

Share to HIV Infections

Share to Receptors, CCR5

Share to Treatment Outcome

Share to Viral Load

Source

Open in PubMed Open full text

Identifiers

PMID: 24714069
DOI: 10.1097/QAI.0000000000000129
PMCID: PMC3996453

Genes

CCR5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

African ancestry influences CCR5 -2459G>A genotype-associated virologic success of highly active antiretroviral therapy.PMID 24714069Read ↗

Chemokine (C-C motif) receptor 5 -2459 genotype in patients receiving highly active antiretroviral therapy: race-specific influence on virologic success.Semantic proximity Read ↗

Race-specific HIV-1 disease-modifying effects associated with CCR5 haplotypes.Semantic proximity Read ↗

Influence of CCR5 promoter haplotypes on AIDS progression in African-Americans.Semantic proximity Read ↗

Associations of Genetically Determined Continental Ancestry With CD4+ Count and Plasma HIV-1 RNA Beyond Self-Reported Race and Ethnicity.Semantic proximity Read ↗

Genetic Variants of APOL1 Are Major Determinants of Kidney Failure in People of African Ancestry With HIVSemantic proximity Read ↗

Multicohort genomewide association study reveals a new signal of protection against HIV-1 acquisition.Semantic proximity Read ↗

Host genetic profiles predict virological and immunological control of HIV-1 infection in adolescents.Semantic proximity Read ↗

CXCR6 gene characterization in two ethnically distinct South African populations and association with viraemic disease control in HIV-1-infected black South African individuals.Semantic proximity Read ↗

Race/ethnicity genotypes associated with HIV-1 antiretroviral therapy.Semantic proximity Read ↗

HAART-associated dyslipidemia varies by biogeographical ancestry in the multicenter AIDS cohort study.Semantic proximity Read ↗

Mitochondrial genomics and CD4 T-cell count recovery after antiretroviral therapy initiation in AIDS clinical trials group study 384.Semantic proximity Read ↗

Host genetic influences on highly active antiretroviral therapy efficacy and AIDS-free survival.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.