Article
Mitochondrial genomics and CD4 T-cell count recovery after antiretroviral therapy initiation in AIDS clinical trials group study 384.
Journal of acquired immune deficiency syndromes (1999) - 1 Dec 2011
Grady Benjamin J, Samuels David C, Robbins Gregory K, Selph Doug, Canter Jeffrey A, Pollard Richard B, Haas David W, Shafer Robert, Kalams Spyros A, Murdock Deborah G, Ritchie Marylyn D, Hulgan Todd
Abstract excerpt
BACKGROUND: Mitochondrial DNA (mtDNA) variation has been associated with time to progression to AIDS and adverse effects from antiretroviral therapy (ART). In this study, full mitochondrial DNA (mtDNA) sequence data from US-based adult participants in the AIDS Clinical Trials Group study 384 was used to assess associations between mtDNA variants and CD4 T-cell recovery with ART. METHODS: Full mtDNA sequence was...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
