Article
Influence of CCR5 promoter haplotypes on AIDS progression in African-Americans.
AIDS (London, England) - 29 Sept 2000
An P, Martin M P, Nelson G W, Carrington M, Smith M W, Gong K, Vlahov D, O'Brien S J, Winkler C A
Abstract excerpt
OBJECTIVES: To test the hypothesis that the CCR5 promoter variants in HIV-1-infected African-Americans affect the rate of progression to AIDS and to determine the extent of linkage disequilibrium between the CCR5P1 allele and the CCR5 59029A variant (referred to here as CCR5-2459A), both of which have been shown independently to accelerate AIDS progression in Caucasians. DESIGN: We used survival analysis to...
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