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Article

Host genetic influences on highly active antiretroviral therapy efficacy and AIDS-free survival.

Journal of acquired immune deficiency syndromes (1999) - 1 Jul 2008

Hendrickson Sher L, Jacobson Lisa P, Nelson George W, Phair John P, Lautenberger James, Johnson Randall C, Kingsley Lawrence, Margolick Joseph B, Detels Roger, Goedert James J, O'Brien Stephen J

Abstract excerpt

We studied the influence of AIDS restriction genes (ARGs) CCR5-Delta32, CCR2-64I, SDF1-3'A, IL10-5'A, CX3CR1-V249I, CX3CR1-T280M, and MDR1-C3435T and haplotypes of the CCR5 P1 promoter and RANTES variants -403A, In1.1C, 3'222C, and -28G among HIV-1 infected patients on highly active antiretroviral therapy (HAART) in the Multicenter AIDS Cohort Study (MACS) and the Multicenter Hemophilia Cohort Study (MHCS). Our...

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Share to Acquired Immunodeficiency Syndrome
Share to Antiretroviral Therapy, Highly Active

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to ATP Binding Cassette Transporter, Subfamily B, Member 1

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Source

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Identifiers

PMID: 18391751
DOI: 10.1097/QAI.0b013e31816fdc5f
PMCID: PMC6986260

Genes

CCR5
CCR2

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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