Article
Genetic Variants of APOL1 Are Major Determinants of Kidney Failure in People of African Ancestry With HIV
25 Jan 2022
Abstract excerpt
Introduction Variants of the APOL1 gene are associated with chronic kidney disease (CKD) in people of African ancestry, although evidence for their impact in people with HIV are sparse. Methods We conducted a cross-sectional study investigating the association between APOL1 renal risk alleles and kidney disease in people of African ancestry with HIV in the UK. The primary outcome was end-stage kidney disease...
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