Article
Transforming growth factor-β1 and α-smooth muscle actin in stromal fibroblasts are associated with a poor prognosis in patients with clinical stage I-IIIA nonsmall cell lung cancer after curative resection.
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine - 1 Jul 2014
Chen Yongbing, Zou Li, Zhang Yongsheng, Chen Yuanyuan, Xing Pengfei, Yang Wentao, Li Feng, Ji Xiaoqing, Liu Fengjv, Lu Xueguan
Abstract excerpt
The aims of this study were to investigate the expression of transforming growth factor-β1 (TGF-β1) and α-smooth muscle actin (α-SMA) in surgical resection specimens from nonsmall cell lung cancer (NSCLC) and to evaluate the prognostic significance of this gene expression in stromal fibroblasts for patients with clinical stage I-IIIA NSCLC. The immunohistochemical expression of TGF-β1 and α-SMA was evaluated in...
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