Article

TGF-β-induced α-SMA expression is mediated by C/EBPβ acetylation in human alveolar epithelial cells in vitro

2020-03-13

Abstract excerpt

<title>Abstract</title> <p>Background This study sought to determine whether binding of acetylated C/EBPβ to α-SMA promoter could affect its activity and was essential for EMT and extracellular matrix deposition in IPF using in vitro model. Methods Through western blotting, the expression of EMT and C/EBPβ were detected in A549 cells with TGF-β as pulmonary fibrotic model in vitro. Moreover, the expression of C/E...

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Literature Corpus work: d275dd6b-3bf8-557a-9fbc-f0d43fa8adc0
DOI: 10.21203/rs.3.rs-17120/v1

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