Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

α11β1 Integrin is Induced in a Subset of Cancer-Associated Fibroblasts in Desmoplastic Tumor Stroma and Mediates In Vitro Cell Migration

1 Jun 2019

Abstract excerpt

Integrin α11β1 is a collagen receptor that has been reported to be overexpressed in the stroma of non-small cell lung cancer (NSCLC) and of head and neck squamous cell carcinoma (HNSCC). In the current study, we further analyzed integrin α11 expression in 14 tumor types by screening a tumor tissue array while using mAb 203E3, a newly developed monoclonal antibody to human α11. Different degrees of expression of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Caveolin-1 and cellular processes
Share to Cell Adhesion Molecules Research
Share to Cellular Mechanics and Interactions

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 31159419
DOI: 10.3390/cancers11060765

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 24 Oct 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

α11β1 Integrin is Induced in a Subset of Cancer-Associated Fibroblasts in Desmoplastic Tumor Stroma and Mediates In Vitro Cell MigrationPMID 31159419Read ↗

Cancer‐associated fibroblast migration in non‐small cell lung cancers is modulated by increased integrin α11 expressionSemantic proximity Read ↗

Integrin α11β1 is expressed in breast cancer stroma and associates with aggressive tumor phenotypesSemantic proximity Read ↗

Integrin α11 regulates IGF2 expression in fibroblasts to enhance tumorigenicity of human non-small-cell lung cancer cellsSemantic proximity Read ↗

Characterization of Distinct Populations of Carcinoma-Associated Fibroblasts from Non–Small Cell Lung Carcinoma Reveals a Role for ST8SIA2 in Cancer Cell InvasionSemantic proximity Read ↗

Integrin α5 subunit is required for the tumor supportive role of fibroblasts in colorectal adenocarcinoma and serves as a potential stroma prognostic markerSemantic proximity Read ↗

Integrins Within the Tumor Microenvironment: Biological Functions and Advances in Therapeutic Targeting <strong> </strong>Semantic proximity Read ↗

Expression of cancer-associated fibroblast related proteins in metastatic breast cancer: an immunohistochemical analysis.Semantic proximity Read ↗

PDGFRβ Is a Novel Marker of Stromal Activation in Oral Squamous Cell CarcinomasSemantic proximity Read ↗

Stromal FAP is an independent poor prognosis marker in non-small cell lung adenocarcinoma and associated with p53 mutation.Semantic proximity Read ↗

Isolation of Normal and Cancer-associated Fibroblasts from Fresh Tissues by Fluorescence Activated Cell Sorting (FACS)Semantic proximity Read ↗

The alpha2beta1 integrin mediates the malignant phenotype on type I collagen in pancreatic cancer cell lines.Semantic proximity Read ↗

Down-regulation of COL1A1 inhibits tumor-associated fibroblast activation and mediates matrix remodeling in the tumor microenvironment of breast cancerSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.