Article
Phenotypic differences of proliferating fibroblasts in the stroma of lung adenocarcinoma and normal bronchus tissue.
Cancer science - 1 Mar 2004
Nakamura Naoko, Iijima Tatsuo, Mase Kentaro, Furuya Shuichiroh, Kano Junko, Morishita Yukio, Noguchi Masayuki
Abstract excerpt
Fibroblasts in tumor tissue are thought to interact with tumor cells directly and/or indirectly and to have important roles in tumor invasion and metastasis. To characterize the phenotype of proliferating fibroblasts in pulmonary adenocarcinoma, we established short-term fibroblast cell lines from both normal bronchus and adenocarcinoma tissues obtained from the same patients and compared the gene expression...
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