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Article

Tumour-derived TGF-beta1 modulates myofibroblast differentiation and promotes HGF/SF-dependent invasion of squamous carcinoma cells.

British journal of cancer - 23 Feb 2004

Lewis M P, Lygoe K A, Nystrom M L, Anderson W P, Speight P M, Marshall J F, Thomas G J

Abstract excerpt

The development of an altered stromal microenvironment is a common feature of many tumours including squamous cell carcinoma (SCC), and there is increasing evidence that these changes in the stroma, which include increased expression of proteases and cytokines, may actually promote tumour progres...

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Topics

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Share to Carcinoma, Squamous Cell
Share to Cell Transformation, Neoplastic
Share to Hepatocyte Growth Factor

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Mouth Neoplasms

Share to Muscle, Smooth

Share to Neoplasm Invasiveness

Share to Stromal Cells

Share to Transforming Growth Factor beta

Source

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Identifiers

PMID: 14970860
DOI: 10.1038/sj.bjc.6601611
PMCID: PMC2410183

Genes

HGF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-14970860-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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