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Article

Transforming Growth Factor-Beta Produced by Non-small Cell Lung Cancer Cells Contributes to Lung Fibroblast Contractile Phenotype.

Anticancer research - 1 Apr 2018

Kanaji Nobuhiro, Yokohira Masanao, Watanabe Naoki, Kadowaki Norimitsu, Bandoh Shuji

Abstract excerpt

BACKGROUND/AIM: Fibroblasts can alter the extracellular matrix (ECM), contributing to cancer progression by providing a scaffold for cancer cells. The influence of lung cancer cells (LCCs) on lung fibroblast-mediated ECM alteration is not well understood. MATERIALS AND METHODS: After incubation in serum-free medium, LCC- or fibroblast-conditioned media were collected. The ECM alteration was assessed by collagen...

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Identifiers

PMID: 29599317
DOI: 10.21873/anticanres.12439

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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