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Article

Fibroblast phenotypes in different lung diseases.

Journal of cardiothoracic surgery - 5 Sept 2014

Du Heng, Chen Dali, Zhou Yubin, Han Zhaojie, Che Guowei

Abstract excerpt

BACKGROUND: The "seed and soil" hypothesis emphasizes the importance of interactions between tumor cells and their microenvironment. CAFs (Cancer associated fibroblasts) are important components of the tumor microenvironment. They were widely involved in cancer cells growth and metastasis. Fibroblasts may also play a role in inflammatory disease. The phenotype conversion of fibroblasts in lung diseases has not...

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Identifiers

PMID: 25189096
DOI: 10.1186/s13019-014-0147-z
PMCID: PMC4173054

Genes

FAP

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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