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Article

AKI after conditional and kidney-specific knockdown of stanniocalcin-1.

Journal of the American Society of Nephrology : JASN - 1 Oct 2014

Huang Luping, Belousova Tatiana, Pan Jenny Szu-Chin, Du Jie, Ju Huiming, Lu Lianghao, Zhang Pumin, Truong Luan D, Nuotio-Antar Alli, Sheikh-Hamad David

Abstract excerpt

Stanniocalcin-1 is an intracrine protein; it binds to the cell surface, is internalized to the mitochondria, and diminishes superoxide generation through induction of uncoupling proteins. In vitro, stanniocalcin-1 inhibits macrophages and preserves endothelial barrier function, and transgenic overexpression of stanniocalcin-1 in mice protects against ischemia-reperfusion kidney injury. We sought to determine the...

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Identifiers

PMID: 24700878
DOI: 10.1681/ASN.2013070690
PMCID: PMC4178431

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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