Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Increased susceptibility to structural acute kidney injury in a mouse model of presymptomatic cardiomyopathy.

American journal of physiology. Renal physiology - 1 Sept 2017

Pleasant LaTawnya, Ma Qing, Devarajan Mahima, Parameswaran Priyanka, Drake Keri, Siroky Brian, Shay-Winkler Kritton, Robbins Jeffrey, Devarajan Prasad

Abstract excerpt

The early events that signal renal dysfunction in presymptomatic heart failure are unclear. We tested the hypothesis that functional and mechanistic changes occur in the kidney that precede the development of symptomatic heart failure. We employed a transgenic mouse model with cardiomyocyte-specific overexpression of mutant α-B-crystallin that develops slowly progressive cardiomyopathy. Presymptomatic transgenic...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Renin
Share to Acute Kidney Injury

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to alpha-Crystallin B Chain

Share to Asymptomatic Diseases

Share to Creatinine

Share to Heart Failure

Share to Lipocalin-2

Share to Reperfusion Injury

Source

Open in PubMed Open full text

Identifiers

PMID: 28679593
DOI: 10.1152/ajprenal.00505.2016
PMCID: PMC5625099

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Increased susceptibility to structural acute kidney injury in a mouse model of presymptomatic cardiomyopathy.PMID 28679593Read ↗

Non-Transgenic Mouse Models of Kidney Disease.Semantic proximity Read ↗

Diabetic kidney lesions of GIPRdn transgenic mice: podocyte hypertrophy and thickening of the GBM precede glomerular hypertrophy and glomerulosclerosis.Semantic proximity Read ↗

Recent Advances in Elucidating the Mechanism Underlying Proteinuric Kidney Disease/Nephrotic Syndrome: Lessons From Knockout/Transgenic Mouse ModelsSemantic proximity Read ↗

Diabetic kidney disease in FVB/NJ Akita mice: temporal pattern of kidney injury and urinary nephrin excretion.Semantic proximity Read ↗

The Goto Kakizaki rat: Impact of age upon changes in cardiac and renal structure, function.Semantic proximity Read ↗

Zebrafish as a Model of Cardiac Pathology and Toxicity: Spotlight on Uremic ToxinsSemantic proximity Read ↗

Tubular overexpression of gremlin induces renal damage susceptibility in mice.Semantic proximity Read ↗

Urinary candidate biomarkers in an experimental autoimmune myocarditis rat modelSemantic proximity Read ↗

A truncated cardiac troponin T molecule in transgenic mice suggests multiple cellular mechanisms for familial hypertrophic cardiomyopathy.Semantic proximity Read ↗

Liver angiotensinogen is the primary source of renal angiotensin II.Semantic proximity Read ↗

A novel mouse model of hypertensive emergency with multiorgan microvascular disease implicating the VEGFA/sFlt-1 balanceSemantic proximity Read ↗

Molecular imaging along the heart-kidney axisSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.