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Article

PKB/SGK-resistant GSK-3 signaling following unilateral ureteral obstruction.

Kidney & blood pressure research - 1 Jan 2013

Voelkl Jakob, Mia Sobuj, Meissner Adrian, Ahmed Mohamed S, Feger Martina, Elvira Bernat, Walker Britta, Alessi Dario R, Alesutan Ioana, Lang Florian

Abstract excerpt

BACKGROUND/AIMS: Renal tissue fibrosis contributes to the development of end-stage renal disease. Causes for renal tissue fibrosis include obstructive nephropathy. The development of renal fibrosis following unilateral ureteral obstruction (UUO) is blunted in gene-targeted mice lacking functional serum- and glucocorticoid-inducible kinase SGK1. Similar to Akt isoforms, SGK1 phosphorylates and thus inactivates...

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Identifiers

PMID: 24685987
DOI: 10.1159/000355763

Genes

SGK1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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