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Article

Genome-wide polygenic scoring for a 14-year long-term average depression phenotype.

Brain and behavior - 1 Mar 2014

Chang Shun-Chiao, Glymour M Maria, Walter Stefan, Liang Liming, Koenen Karestan C, Tchetgen Eric J, Cornelis Marilyn C, Kawachi Ichiro, Rimm Eric, Kubzansky Laura D

Abstract excerpt

BACKGROUND: Despite moderate heritability estimates for depression-related phenotypes, few robust genetic predictors have been identified. Potential explanations for this discrepancy include the use of phenotypic measures taken from a single time point, rather than integrating information over longer time periods via multiple assessments, and the possibility that genetic risk is shaped by multiple loci with small...

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PMID: 24683521
DOI: 10.1002/brb3.205
PMCID: PMC3967544

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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