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Article

A polygenic risk score associated with measures of depressive symptoms among older adults.

Biodemography and social biology - 1 Jan 2014

Levine Morgan E, Crimmins Eileen M, Prescott Carol A, Phillips Drystan, Arpawong Thalida E, Lee Jinkook

Abstract excerpt

It has been suggested that depression is a polygenic trait, arising from the influences of multiple loci with small individual effects. The aim of this study is to generate a polygenic risk score (PRS) to examine the association between genetic variation and depressive symptoms. Our analytic sample included N = 10,091 participants aged 50 and older from the Health and Retirement Study (HRS). Depressive symptoms...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 25343367
DOI: 10.1080/19485565.2014.952705
PMCID: PMC4298361

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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